Method document
Sample size to estimate Cohen’s kappa
How many participants two raters must both rate, yes or no, to estimate their agreement beyond chance, Cohen’s kappa, within a chosen margin. Covers non-response.
https://statwisely.com/methods/precision-kappa/
When to use it
- Inter-rater agreement on a binary judgement, such as the presence of a sign on examination, reported with a confidence interval.
Not for
- A rating of several categories, or ordered ones; this planner is for a yes/no rating.
Notation
- Number of participants rated by both raters
- Expected kappa
- Share of ratings that are “yes”, the same for both raters
- Variance of kappa per participant
- Margin of error
- Standard normal quantile for confidence 1 − α (1.960 for 95%)
- Non-response rate
Formulas
Participants from the variance of kappa
V is the large-sample variance of kappa when both raters say “yes” with probability p [1]. It grows as “yes” becomes rare or nearly universal, which is why kappa is hard to estimate for uncommon findings.
Non-response
The number to approach so that n respond. Applied last, after any clustering.
Parameters
Confidence level
Values: 90%, 95% or 99%
95% is the convention in health research. A higher level widens the interval, so the same margin needs a larger sample.
Margin of error
Values: Above 0 and below 1
Half the interval’s width on the coefficient’s scale: 0.1 gives an interval from 0.5 to 0.7 around a kappa of 0.6.
Expected kappa
Values: Between 0 and 1
From a pilot or published agreement studies of similar raters.
Share rated “yes”
Values: Between 0 and 1
How common the finding is among those to be rated.
Expected non-response rateOptional
Values: 0% up to, but not including, 100%
The share of people approached who will not take part; use the response rate of a comparable study. Approaching more people restores the number of respondents, not their representativeness: if non-responders differ, the estimate can still be biased.
Assumptions
- Each participant is rated once by each of two raters, who say “yes” equally often; participants are independent.
- Non-response is unrelated to the outcome.
Worked examples
A finding in three in ten
Kappa 0.6 within ±0.1 with 0.3 rated “yes”: V = 0.4 × (−0.08 + 0.84/0.42) = 0.768, so n = 1.96² × 0.768 / 0.1² = 295.0, rounded up to 296.
Sample size: 296
Open this example in the calculatorAn even split
With 0.5 rated “yes”, the most informative case: n = 246.
Sample size: 246
Open this example in the calculatorValidation
- Every worked example on this page is recomputed by the StatWisely engine whenever the software is built. If a number or formula here stopped matching the calculator, the release would be stopped until this document was corrected.
- Kappa from simulated two-rater tables at the planned size varied with a standard deviation that gives a 95% half-width of 0.100 against a target of 0.10. An independent implementation in R recomputes these sizes and is compared with the engine’s.
How to cite
StatWisely. Sample size to estimate Cohen’s kappa. Method document, engine version 1.0.0, reviewed 2026-10-09. https://statwisely.com/methods/precision-kappa/
Cite the original references for the formulas your design uses as well.
References
- 1.Bloch DA, Kraemer HC. 2 × 2 kappa coefficients: measures of agreement or association. Biometrics. 1989;45(1):269–287.